Not necessarily. When I was writing the initial comment I wasn't even thinking about job-related mails, but at someone like Sean Carroll who does a regular Ask me Anything [1] where lots of questions are skipped for lack of time, or in general academics who receive plenty of emails about articles and various field-related questions.

[1] at the beginning of each month, May 2023 https://www.youtube.com/watch?v=h_GD4E27Bt8