I recently switched our Python projects to uv and it love it. It just does everything and is really fast (this just cannot be underestimated in what it means for your workflow).
I've tried almost every Python packaging solution under the sun in the past 15 years but they all had their problems. Finally I just stuck with pip/pip-tools and plain venv's but strung together with a complicated Makefile to optimize the entire workflow for iteration speed (rebuilding .txt files when .in requirements changes, rebuilding venv if requirements change, etc). I've been able to reduce it to basically one Make target calling uv to do it all.
I've tried almost every Python packaging solution under the sun in the past 15 years but they all had their problems. Finally I just stuck with pip/pip-tools and plain venv's but strung together with a complicated Makefile to optimize the entire workflow for iteration speed (rebuilding .txt files when .in requirements changes, rebuilding venv if requirements change, etc). I've been able to reduce it to basically one Make target calling uv to do it all.