I used to have the same setup - a global tools venv with some useful dependencies.

Uv takes the position that since it’s so fast to install dependencies and create environments, you don’t maintain a global venv.

  uvx ruff file.py

Will setup a venv, install ruff into it, and run over your file. https://docs.astral.sh/uv/guides/tools/

Otherwise you can:

  uv run —-with package file.py

If you don’t want to declare your dependencies.

https://docs.astral.sh/uv/guides/scripts/#running-a-script-w...