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Existing as in another lab created that mutation or existing as in that mutation evolved naturally in the wild?


Per the paper, found in the wild.

> We isolated an HPAI H5N1 clade 2.3.4.4b virus from wild birds in Korea with 96% E and 4% K at amino acid position 627 of PB2. To investigate the genomic characteristics of this clade regarding mammalian adaptation, we studied the replication and transmission of the H5N1 virus in mice.




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