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Cheese Consumption and Dementia in Older Japanese Adults: The Jages Cohort Study (mdpi.com)
27 points by gnabgib 50 days ago | hide | past | favorite | 11 comments


From the abstract:

> Conclusions: Habitual cheese consumption (≥1 time/week) was modestly associated with a reduced 3-year incidence of dementia in older Japanese adults. [Absolute risk difference of 1.06 percentage points.] While the absolute risk reduction was small, these findings are consistent with prior observational evidence linking dairy intake to cognitive health. Further research is warranted to clarify dose–response relationships, cheese subtypes, and underlying mechanisms.


This is surprising. You'd expect cholesterol to accumulate in the blood vessels in the brain and create problems.


The blood vessels in the brain prevent cholesterol from passing through due to the blood-brain barrier.

The first part of this abstract breaks down the current understanding nicely: https://www.mdpi.com/1467-3045/47/2/115


Then how come you start forgetting things when your cholesterol gets way high, like 4x the reference/normal value?


Just speculating, but if your cardiovascular function degrades due to cholesterol, it should have an impact on the brain.


That's actually a good idea, thanks.


TIL! Thank you.


But dietary cholesterol is not linked to cholesterol in the blood vessels

> We confirm from the review of the literature on epidemiological data, meta-analysis, and clinical interventions where dietary cholesterol challenges were utilized that there is not a direct correlation between cholesterol intake and blood cholesterol.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9143438/#abstract1


Cheese is very high in saturated fats, which are linked to blood cholesterol (LDL).

That said, Japanese cuisine is generally low in saturated fats, and adding 1+ instance of cheese per week is unlikely to tip it over doctor-un-recommended levels of sat. fat intake. Especially compared to the standard American diet.


Dietary cholesterol amount is not indicative of risk, unfortunately. I don't know why people keep repeating this. The body produces almost a gram of cholesterol a day, dietary cholesterol is around a quarter of that (depending on the person); if you try interfering with cholesterol production and somehow halt it, you will die.

_Quality_ of dietary cholesterol is indicative of risk, but only a relatively small one, as the things that lead to damaged dietary lipoproteins also damages the endogenous ones as well (ie, ultra-processed foods, the chemicals in them try to ultra-process you too).

Eating less cholesterol doesn't magically make your food good for you, and the average public shouldn't be continually told this.


Kind of wonder if it some component like calcium




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